Chloral hydrate anesthesia in mice

Author: jxzs

August undefined, 2024

WebGroups were uninfected pregnant mice (G1); untreated infected pregnant mice (G2), infected pregnant mice treated with AS201-01 (G3), and infected pregnant mice treated with DHP tablet (G4).

Impacts of Different Anesthetic Agents on Left Ventricular Systolic ...

WebHepatic enzyme analysis: Chloral hydrate did not significantly induce either lauric acid 4-hydroxylase activity or CYP4A immunoreactive protein in any of the dosed groups of ad libitum-fed mice. However, 100 mg/kg did significantly induce both lauric acid 4-hydroxylase activity and CYP4A immunoreactive protein in the dietary-controlled mice. WebJun 12, 1998 · Chloral hydrate is a hepatocarcinogen in mice but not rats. To examine this species-related difference, male and female B6C3F1 mice and Fischer (F344) rats were treated by gavage with 1 or 12 doses of chloral hydrate, and concentrations of the drug and its metabolites were determined in plasma at 0.25, 7, 3, 6, and 24 h and 2, 4, 8, and 16 d … alfieri scrittore

A review of laboratory animal anesthesia with chloral

WebSep 30, 2013 · The mice used in this study were between 6 weeks and 4 months of age and were on a randomly mixed genetic background comprised of C57BL/6J and 129 Sv/Ev … WebAll surgery was performed under chloral hydrate anesthesia, and all efforts were made to minimize suffering. ... All mice were sacrificed under chloral hydrate anesthesia at day 21 after the first injection. Tumor nodules in the abdominal cavity were collected and weighed; mice weight and ascites were also evaluated in all groups. WebChloral hydrate has been used in human and veterinary medicine as a sedative and hypnotic drug since the mid-19th century. Chloral hydrate's effects are primarily caused by its active metabolite trichloroethanol. Chloral hydrate is primarily a hypnotic and has little or no analgesic effect. In candidates for surgery, it is a satisfactory ... mini r56 オイル漏れ修理費用

Chloral Hydrate Anesthesia and Lens Opacification in Mice

WebChloral hydrate is regarded by many to produce hypnosis and not anesthesia.2It does not provide analgesia and causes marked respiratory depression at doses required for surgical anesthesia.3Apart from its … WebJan 12, 2015 · The mice were housed and fed in an air-conditioned room on a 12-h light/dark cycle in a standard laboratory. ... the mice were injected intraperitoneally with 4.3% chloral hydrate (430 mg/kg, Pharmacy ... prior to intravitreal injection of mini-αA. After anesthesia, compound tropicamide eye drops (Shenyang Xingqi Pharmaceutical Co., … alfieri scuola mediaWebJul 1, 1993 · Some studies (55,56) use 300-400 mg/kg chloral hydrate to perform surgery or establish animal models, the process of which requires deep anesthesia and long duration. ... alfieri ritratto

"WebFeb 17, 2009 · Anaesthesia was induced by chloral hydrate (500 mg kg −1, i.p.), and mice were killed 10 min after drug injection. Control mice received a PBS injection. Control mice received a PBS injection. Representative immunoblots are shown left to … " - Chloral hydrate anesthesia in mice

Chloral hydrate anesthesia in mice

Toxicology and carcinogenesis study of chloral hydrate (ad …

WebJul 1, 1993 · Some studies (55,56) use 300-400 mg/kg chloral hydrate to perform surgery or establish animal models, the process of which requires deep anesthesia and long duration. ... WebWe show that chloral hydrate, when used intraperitoneally, induces acute and reversible lens opacification in all animals. In addition, we found that instillation of hypromellose …

Did you know?

WebJul 19, 2024 · PDF The present experiments were performed to study the effects and time trends of different anesthetic agents on the left ventricular (LV) systolic... Find, read and cite all the research you ... Webmoethanol or fentanyl-fluanisone-diazepam anesthesia. However, a small but significant degree of radioprotection was observed under chloral hydrate or pentobarbital anes- ... (iii) Chloral hydrate: 2,2,2-trichloro-1,1-ethanediol (chloral hydrate by B.D.H. Chemicals Ltd.). The mice were boxed 5 min after an intraperitoneal injection of 300 mg/kg ...

WebPurpose: To study the effect of chloral hydrate in the eye lens in mice.Methods: We instilled tropicamide in the eyes of two groups of eight 129 strain wild-type mice and … WebDec 1, 2013 · To explore effect of different anesthesia methods and different anesthetics on erythrocyte immune function in mice. Methods. The mice were anesthetized by isoflurane and ether inhalation, and also under intraperitoneal anesthesia with sodium pentobarbital and chloral hydrate. Blood was collected from the ventro-cardinal vein.

WebHome Research A to Z WebJan 10, 2024 · Chloral hydrate . 400 mg/kg IP . Unproven . Non-survival procedures . Tribromoethanol . 125 - 250 mg/kg IP . 30 - 45 minutes . Avoid re-dosing ... Spaeni D, …

WebPurpose: To study the effect of chloral hydrate in the eye lens in mice.Methods: We instilled tropicamide in the eyes of two groups of eight 129 strain wild-type mice and injected chloral hydrate intraperitoneally (400 mg/kg). A drop of hypromellosum solution was additionally instilled in the eye of the second group to reduce corneal dehydration. The …

WebMay 1, 2024 · 1302 Purpose: To evaluate the effect of different concentrations of chloral hydrate and isoflurane anesthesia on brain uptake of 18F-FDG in mice. Methods: Total … alfieri riassunto breveWebJun 1, 2009 · The mice of Groups A and D were injected by 4% chloral hydrate solution to anesthesia. The dose was 10 mL/kg [8, 19] . The mice in Groups B and E exposured to … alfieri scuola bolzanoWebMar 5, 2009 · For surgery and microinjection, chloral hydrate-anesthetized mice were positioned in a stereotaxic apparatus (NARISHIGE Scientific Instrument LAB); the lentivirus filled in the glass electrode was injected aiming at PAG (AP-4.5 mm; ML ±0 mm; DV 2mm). Lentivirus (1.5 μL) was microinjected into the PAG at a rate of 0.15 μL/min. mini r56 パーツリストWebProcedures: Sixty-minute dynamic [18 F] FDG PET scans were performed in adult male C57BL/6 mice anesthetized with isoflurane [control (in 100 % O 2), in medical air, in 100 % O 2 + insulin pre-treatment, and in 100 % O 2 after 18 h fasting], ketamine/xylazine, sevoflurane, and chloral hydrate. An additional group was scanned after awake uptake. alfieri scuola romaWebOct 1, 2014 · Naïve mice and animals with acute traumatic brain injury induced by controlled cortical impact (CCI) were randomized to the following euthanasia protocols (n=10-11/group): no anesthesia (NA), 1 min of 4 vol% isoflurane in room air (ISO), 3 min of a combination of 5 mg/kg midazolam, 0.05 mg/kg fentanyl, and 0.5 mg/kg medetomidine ... alfieri sergioWebAll mice were intraperitoneally injected (10 mL·kg −1) with a 4% chloral hydrate solution for anesthesia. For ALI model group, the mice were instilled with 50 μL of LPS solution at a concentration of 1.5 mg·mL −1. (Dose was 3 mg·kg −1); the mice in the blank control group were instilled with the same volume of normal saline, and the ... mini r56 バックランプ ledWebMay 31, 2024 · It is worth noting that adverse side effects similar to those reported after TBE administration occur after i.p. administration of chloral hydrate and alpha-chloralose 23. … alfieri scuola torino